ABSTRACT
Thrombocytosis is commonly seen in reactive conditions and certain neoplastic states, such as chronic myeloproliferative disorders. It is rarely seen in acute leukemia. A 12-year-old girl with acute myeloblastic leukemia (FAB M2) in remission presented with pyoderma. Her hemogram revealed anemia (Hb-6.4g/dl), leucopenia (TLC - 1.2 x 109/L) and thrombocytosis (platelet count- 580 x 109/L). A peripheral blood film showed numerous abnormally large platelets with few atypical cells. The thrombocytosis subsided with the clearance of infection but atypical cells persisted. One month later, she relapsed. Cytogenetic analysis revealed variable results (trisomy 9 and deletion 3). This case has been presented because thrombocytosis is rare in AML and its appearance calls for a close follow-up.
Subject(s)
Anemia/etiology , Child , Female , Humans , Leukemia, Myeloid, Acute/complications , Pyoderma/etiology , Thrombocytosis/pathologyABSTRACT
Os autores fazem uma revisão bibliográfica da etiopatogenia, imunidade, diagnóstico e tratamento das principais manifestações dermatológicas causadas por Streptococcus pyogenes e Staphylococcus aureus
Subject(s)
Humans , Pyoderma/diagnosis , Pyoderma/etiology , Pyoderma/physiopathology , Streptococcal Infections/transmission , Skin Diseases, Infectious , Staphylococcus aureus/pathogenicity , Streptococcus pyogenes/pathogenicitySubject(s)
Humans , Male , Female , Pyoderma/etiology , Streptococcus pyogenes , Staphylococcus aureus , ChildABSTRACT
Se estudió a 123 niños, en los que se sospechó la exsitencia de sarna, frente a los siguientes hallazgos clínicos: prurito de inicio insidioso o no, erupción cutánea, y las características epidemiológicas típicas. Se consideró recientes a los casos que presentaron un tiempo de evolución inferior a 30 días (57 niños), y a los restantes (65 pacientes), de evolución prolongada. Las edades oscilaron entre 1 y los 120 meses. En 113 niños (91,9 por ciento ), la erupción cutánea fue el hallazgo más fercuente. Prurito se manifestó en 99 pacientes, en tanto que infección de otros contactos en 92 casos (74 por ciento ). En 71 (57,7 por ciento ) niños, sólo se presentó sarna exclusivamente, en 24 (19,5 por ciento ) se asoció a infección bacteriana, en 18 (14,6 por ciento ) a hipersensibilidad y sarna, infección bacteriana e hipersensibilidad en 10 (8,2 por ciento ). Los gérmenes que más frecuentemente se aislaron fueron de S. aureus en 11 casos, y la asociación de S. pyogenes en lo de ellos. El Acaro test tuvo un rendimiento global de un 20,3 por ciento (25 niños), presentando su mayor utilidad en los casos de larga evolución, en que no se aplicó acaricidas previamente (33,3 por ciento ). De los antisárnicos utilizados, el lindano al 1 por ciento tuvo un rendimiento de 75 por ciento (48 niños), el crotamitón al 10 por ciento en loción, de 94,9 por ciento (47 pacientes) y la vaselina azufrada al 5 por ciento de 77,8 por ciento (7 casos). Se destaca la eficiencia del crotamitón en loción en esta patología
Subject(s)
Humans , Infant , Child, Preschool , Child , Adolescent , Ectoparasitic Infestations/parasitology , Sarcoptes scabiei/pathogenicity , Scabies/parasitology , Pyoderma/etiology , Sarcoptes scabiei/isolation & purification , Scabies/complications , Scabies/therapyABSTRACT
We present a patient with pyoderma gangrenosum, a rare complication of ulcerative colitis. The patient's disease was limited to the distal colon, was clinically mild and responded quickly to treatment, and yet it was associated with pyoderma gangrenosum and arthritis, complications generally associated with more severe and extensive ulcerative colitis.
Subject(s)
Abdominal Muscles/pathology , Adult , Colitis, Ulcerative/complications , Gangrene , Humans , Male , Pyoderma/etiologyABSTRACT
One hundred and fifty patients of idiopathic ulcerative colitis were studied for extraintestinal manifestations by clinical, radiological and biochemical means. One or more such manifestations occurred in 34.7% of patients. Sacroiliitis (14%) and peripheral arthritis (10.7%) were the commonest manifestations, followed by ocular (8%), mucocutaneous (2.7%), vascular (2%) and hepatobiliary (1.3%) manifestations. We conclude that the incidence and spectrum of extraintestinal manifestations in Indian patients with idiopathic ulcerative colitis are similar to those in western patients.
Subject(s)
Adolescent , Adult , Arthritis/etiology , Colitis, Ulcerative/complications , Eye Diseases/etiology , Female , Humans , India , Male , Middle Aged , Prospective Studies , Pyoderma/etiology , Recurrence , Sacroiliac Joint , Stomatitis, Aphthous/etiology , Thrombophlebitis/etiologyABSTRACT
Relatam-se casos de retocolite ulcerativa idiopática, que durante a evoluçäo apresentaram três das mais temíveis complicaçöes: pioderma gangrenoso, megacólon tóxico e a degeneraçäo carcinomatosa do cólon